- Amino acids were designed considering various interactions with antigens according to analyzing the CDR sequences of human-derived antibodies.
- Optimized CDR considering physicochemical stability and productivity + Human FR with verified physicochemical properties and productivity.
- The optimal antibody library based on various library production experiences.
- Experience in successfully discovering antibodies for over 30 types of high-difficulty antigens, including GPCRs and immune checkpoints.
- Diverse engineering experience and skills of rational engineering and directed-evolution.
(Granting selectivity, Granting pH-dependent binding ability, Regulating agonism, affinity maturation, etc.)